What Happens When You Overdose on Truvada?

Get answers on questions about how to take Truvada safely to ensure that you get all the benefits without any unnecessary risks and complications. Be informed on what happens if you accidentally take a double dose of Truvada as well as helpful tips on how to take medications correctly for high efficacy and tolerability.

Adhering to drug prescription is the best bet to stay safe and ensure the effective working of the med in the body. Overdose can cause unavoidable health conditions that may demand medical attention.

How can you ensure you consistently take your meds every day without overdose? It turns out we have a detailed plan. Read on for full info on Truvada administration safely to guarantee higher efficacy and tolerability.

😵Can You Overdose on Truvada for PrEP?

The goal of taking Truvada for PrEP is to cut the risk of HIV infection. Strictly take these tabs as prescribed. You will not receive more protection by taking more than your prescription states. It can lead to an overdose.

Overdose of Truvada may be difficult to distinguish from regular side effects. If these side effects abruptly change in severity and you know you’ve taken too much, you should seek immediate medical attention [1].

Common symptoms of overdose include:

  • diarrhea, upset stomach, and vomiting;
  • fatigue;
  • headache;
  • dizziness.

Since Truvada can damage kidney or liver function in certain individuals, some symptoms can indicate a serious complication from Truvada overdose. If you experience these symptoms, call your medical specialist [2].

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🤔Accidental Double Dose of Truvada: What to Do Next?

Most patients are very careful when taking Truvada (only 1 tab at the same time every day), but what if you take your pill twice in the same day? This accidental double dose is something that you may experience – probably due to a delayed or forgotten dosage.

If you are aware of a double dose, closely watch your condition for any side effects, such as the ones listed above. If you cannot get in touch with your doctor right away, it is best to be cautious and go to the hospital at once to ensure that everything is okay.

Some patients wrongly think that if they forget to take their pill on one day, they should take two pills the next day. This can lead to overdose symptoms and be potentially dangerous to your kidneys or liver.

Taking this med at about the same time every day to ensure that the levels of medicine reach a steady-state in your bloodstream. Don’t try to make up for a missed dose.

✔Taking Medication for HIV Prevention Correctly

It can be easy to forget to take your daily tab. At HIVPrEP, we’ve come up with some simple ways you can use to avoid missing doses or taking that accidental double dose [3].

These tips will help you keep your Truvada levels safe and consistent for the long term, giving you the best chance to avoid HIV infection and overdose:

  • learning and understanding about your medication (and especially about side effects) will give you the knowledge needed to adhere to your doctor’s plan for your care;
  • using a pillbox. It’s not only for older people. They are a simple tool that makes it easy to see if you’ve taken your medication for the day;
  • utilize smartphone apps like a calendar (with daily reminders) to help you track and remember to take your pills at the right time [4];
  • establish a routine such as taking your med as the first thing in the morning, or before bed;
  • utilize your support network. Ask your friends or family for help with staying on track. If it’s appropriate, you can have them ask or text you every day to check if you’ve taken your daily dose.

What’s more? Those are some of the tips you need to understand while taking any medication according to your doctor’s plan. You don’t want to lose the benefits of taking the medication by forgetting doses, and you certainly want to avoid an accidental overdose.


  1. Truvada (emtricitabine and tenofovir disoproxil fumarate). Healthline.com.
  2. What are the side effects of taking 2 doses of Truvada at the same time? By Erockdw. Retrieved 28 Jul. 2010. Drugs.com.
  3. How to Organize Your Medications.Webmd.com.
  4. The 5 Best Reminders for Your Medications. Healthline.com.
Logan Morris

Expert in pharmaceutical practice and antiviral medicine, founder of HIVPrEP. Main goal is to popularize HIV topics and create awareness for global masses on how to prevent the disease and how to use HIV medication safely.

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