Isentress (Raltegravir) + Prezcobix (Darunavir and Cobicistat)

It is worthy of note that Isentress and Prezcobix have no known disastrous interactions. Thus, they can be taken simultaneously without any short or long term negative effects.

Main Information About Isentress

Isentress is a very popular medication that is used to treat HIV in adults and children. Its active component is raltegravir, and it is responsible for a major part of the action of the drug. It works by preventing the virus from multiplying in the human body. This way, it boosts the immune system.

However, it should be pointed out that Isentress does not cure HIV [1]. Rather, it blocks the actions of the virus and subsequently reduces the viral load in the patient’s blood.

This medication should be used according to a doctor’s prescription. It should be taken orally with or without food. In the same vein, patients using this drug should avoid skipping doses.

What Is Prezcobix?

Prezcobix is another antiretroviral meditation that shares some similarities with Isentress but also possesses some distinctive features as well. These tabs are actually a combination of two different drugs known as darunavir and cobicistat [2]. These two substances join forces to combat the virus.

Darunavir belongs to a category of medications called protease inhibitors. They prevent the replication of the virus purely by selectively binding to viral protease.

On the other hand, cobicistat is a follow-up component that helps increase the level of darunavir in the patient’s body.

Prezcobix is taken orally and regularly based on the doctor’s instructions. It is highly recommended that patients properly consult a doctor before using this medication.

Drug Interaction: Prezcobix and Isentress

Isentress (raltegravir) and Prezcobix (darunavir/cobicistat) can be combined and used together to fight HIV infection.

Trials carried out on possible interactions between the contents of both drugs reveal that there lies a potential for raltegravir to decrease the plasma concentrations of darunavir. The trials also show that this interaction may be clinically irrelevant [2], which means this interaction does not affect the treatment process in a negative way.

Patients are advised to visit a doctor or general health care provider before combining these medications. In the same vein, patients who suffer from severe allergies should let their doctor know about their medical history. This would help in providing alternatives.


  1. Raltegravir.
It may be useful for you